Pharmaceutical Letrozole 2.5mg x 28


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Pharmaceutical Letrozole 2.5mg

Aromatase Inhibitor for Breast Cancer Treatment
Active substance: Letrozole
Form: 2.5mg
Active half-life: 2-4 days
Common side effects: Hot flashes, joint pain, fatigue
Storage: Keep in a cool, dry place

What is Pharmaceutical Letrozole 2.5mg?

Pharmaceutical Letrozole 2.5mg is a medication primarily used to treat breast cancer in postmenopausal women. It belongs to a class of drugs known as aromatase inhibitors, which work by reducing the amount of estrogen produced in the body. This reduction in estrogen levels can help slow or reverse the growth of hormone receptor-positive breast cancers. Each pack contains 28 tablets, providing a month’s supply of the medication.

Mechanism of Action

Letrozole works by inhibiting the aromatase enzyme, which is responsible for converting androgens into estrogen. By blocking this conversion, Letrozole significantly lowers estrogen levels in the body. Since certain types of breast cancer cells rely on estrogen to grow and multiply, reducing estrogen levels can slow down or halt the progression of the disease.

Indications for Letrozole

Letrozole 2.5mg is indicated for the treatment of hormone receptor-positive breast cancer in postmenopausal women. It is often used as a first-line treatment for advanced breast cancer and as an adjuvant therapy following surgery to prevent cancer recurrence. Additionally, it may be prescribed for extended adjuvant treatment in patients who have completed 5 years of tamoxifen therapy.

Dosage and Administration

The recommended dosage of Letrozole is one 2.5mg tablet taken once daily, with or without food. It is important to take the medication at the same time each day to maintain consistent blood levels. Patients should follow their healthcare provider’s instructions and continue taking Letrozole for the prescribed duration, which may be several years.

Efficacy and Clinical Studies

Clinical studies have demonstrated the efficacy of Letrozole in reducing the risk of breast cancer recurrence and improving survival rates in postmenopausal women with hormone receptor-positive breast cancer. Studies have shown that Letrozole can significantly lower the levels of circulating estrogen, leading to better outcomes in both early and advanced stages of the disease.

Side Effects of Letrozole 2.5mg

While Letrozole is effective, it can cause side effects. Common side effects include hot flashes, joint pain, fatigue, and night sweats. Some patients may experience bone thinning (osteoporosis) due to prolonged estrogen suppression. Less common but serious side effects can include cardiovascular events and liver dysfunction. Patients should report any unusual symptoms to their healthcare provider.

Monitoring and Follow-Up

Regular monitoring is essential for patients taking Letrozole. This includes periodic blood tests to check liver function, bone density scans to monitor bone health, and regular follow-up appointments with the healthcare provider to assess the effectiveness of the treatment and manage any side effects.

Contraindications and Precautions

Letrozole is contraindicated in premenopausal women, pregnant women, and those with a known hypersensitivity to the drug. It should be used with caution in patients with a history of cardiovascular disease or osteoporosis. Women of childbearing potential should use effective contraception while taking Letrozole.

Drug Interactions

Letrozole can interact with certain medications, potentially altering its effectiveness or increasing the risk of side effects. Patients should inform their healthcare provider of all medications, supplements, and herbal products they are taking. Notable interactions include estrogen-containing therapies and certain anti-epileptic drugs.

Storage Instructions

Store Letrozole 2.5mg tablets in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use the tablets past their expiration date, and dispose of any unused or expired medication properly.

How to Buy Letrozole 2.5mg Online

Letrozole 2.5mg can be purchased from various online pharmacies and specialized medical suppliers. When buying online, ensure the seller is reputable and the product is genuine. Look for customer reviews, secure payment options, and proper licensing to make an informed purchase.

Patient Support and Resources

Many organizations and support groups are available to help patients undergoing treatment with Letrozole. These resources can provide valuable information, emotional support, and practical advice for managing side effects and maintaining quality of life during treatment. Patients are encouraged to seek out these resources for additional support.

Comparing Letrozole with Other Aromatase Inhibitors

Letrozole is one of several aromatase inhibitors available for the treatment of hormone receptor-positive breast cancer. Other medications in this class include Anastrozole and Exemestane. While all three are effective, differences in side effect profiles and individual patient responses may make one more suitable than another. Healthcare providers will help determine the best option based on the patient’s specific circumstances.


Pharmaceutical Letrozole 2.5mg is a highly effective treatment for hormone receptor-positive breast cancer in postmenopausal women. Its ability to significantly reduce estrogen levels makes it a valuable tool in both early and advanced stages of breast cancer. While generally well-tolerated, patients need to adhere to prescribed dosages, report any side effects, and attend regular follow-up appointments to ensure the best possible outcomes. Always purchase from reputable sources to guarantee the authenticity and quality of the product.